Nick Fury Sr in Fantastic Four #292

Probably one of my favourite issues, for the last panel alone. Nick Fury goes back in time to 1936, in order to assassinate Hitler. A noble cause, but unfortunately would've had even worse ripple effects down time.  He is captured by the Nazis, stripped down to his 1986 Jockey shorts, and presumably tortured for information. But luckily Sue Storm rescues him. 

And quite possibly the best page in comics:

 A sexy guy wearing big white briefs, shooting Hitler at point blank range. It doesn't get any better than that.